Find here the list of best IVF doctors in India on the basis of Ratings, Success Rate, Services offered, IVF cost packages and available Facilities. Dr. Nisha Bhatnagar, Dr. Kaberi Banerjee and Dr. Anjali A Deval top the list of such IVF doctors in India due to their unique pricing system, popularity and high success rate.
ICSI procedure step by step is performed in infertility treatments. ICSI treatment benefits are in case of past IVF failures, trying pregnancy after vasectomy procedure, and for men with low sperm motility and count. ICSI treatment side effects are possible damage to embryo, multiple births, and occurrence of gestational diabetes in mother.
Let’s Discuss in More Detail About What is ICSI:
- What is ICSI?
- When to Go for ICSI?
- What Are the Health Concerns When Planning for Icsi?
- How to Retrieve Sperm for Icsi Use?
- What Does ICSI Procedure Involve?
- How Long Does Icsi Treatment Take?
- What to Expect After ICSI?
- What Is the Success Rate of ICSI Treatment?
- What Are the Risks & Benefits of ICSI?
Intracytoplasmic sperm injection (ICSI) is getting momentum with its high success rates all over the globe. Nowadays, ICSI has been seen getting used in nearly half of the IVF treatments done worldwide. ICSI is used for male infertility issues and improves the chances of conception. (1) (2)
The best thing about ICSI is that it is a very clear-cut procedure. Under this procedure, only one sperm is used and injected directly into the ovum/egg. Here, utmost importance is given to find the best sperm so that it can successfully fertilize the egg. After fertilization, the fertilized egg or the embryo is transferred into the uterus with ART (Assisted Reproductive Technology) techniques. (3)
One should opt for ICSI treatment after proper consultation and recommendation from a doctor or medical professionals. Below are some of the situations under which you may be recommended to get ICSI done if you are looking for a baby (4) (5)-
- Men with a very low sperm count.
- If you have Poor Sperm Morphology (A high range of abnormally shaped and slow-moving sperm).
- Men with Retrograde Sperm Ejaculation issues. Under this situation men can’t ejaculate naturally through urethra and semen flows to the urinary bladder. With ART methods such as TESA, MESA, TESE, etc. sperm is directly collected from the epididymis and ICSI is recommended mostly in such situations.
- Men with Azoospermia (zero sperm in ejaculation) are also recommended ICSI.
- Men with problems in erection and ejaculation due to various health issues.
- After an IVF history with no or low rate of fertilization.
- Women with a low yield of eggs during egg retrieval.
When you are considering ICSI, then you must keep in mind some of the important things related to the procedure. (6)
According to several studies, it is found that the pregnancies achieved via artificial insemination and particularly through IVF can result in having birth defects like imprinting defects.
- Imprinting indicates a phenomenon where certain genes of baby functions differently. It depends whether it involves a particular chromosome passed to a baby by the father or by the mother.
- According to the reproductive researchers, it might affect the imprinting process or the subsequent release due to the manipulation of gametes or zygotes. While other researchers believe the incidence of birth defects keep occurring is similar to that of natural pregnancy thus, doesn’t create any obstacle in using such procedures.
- It is advised to discuss with your reproductive specialist about the potential risks and complications involved in performing ICSI process.
- While some people want to look for more traditional or over the counter methods before opting an infertility procedure. If you need assistance in the decision-making process then you can connect with the Largest Fertility Assistant OVO Fertility.
If a man had the vasectomy done, then for restoring fertility the cost-effective method is microsurgical vasectomy reversal.
- The other alternatives are needle aspiration or microsurgical sperm retrieval i.e. MESA, TESA, if competent microsurgical vasectomy reversal procedure has failed.
- In needle aspiration, the physician obtains the required number of sperms for the ICSI process more easily and quickly. A tiny needle is used for sperm extraction directly from the testis.
This method is an easy and simple process, which is performed under sedation with minimum discomfort. But there is a possibility of pain and swelling once the procedure is done. The sperm collected from the testis is only suitable for the ICSI process.
The ICSI procedure takes place during the IVF procedure. Normally, it is performed for couples who face severe male factor infertility and have a history of IVF failure.
The step-by-step procedure for ICSI discussed in detail are-
1- Ovarian stimulation- the ovaries of the woman are stimulated with medicines to help the growth of follicles. The response of the ovaries and final maturation of the eggs are monitored.
2- Retrieval of eggs- the mature eggs are retrieved within 35-38 hours under sedation.
3- Sperm selection- one healthy sperm with high motility is selected for insemination.
4- Assessment of eggs- the eggs are surrounded by cumulus cells which are removed through delicate enzyme so that they can be finally prepared for the insemination.
5- Insemination- this is the main step of ICSI where a single sperm is injected into the matured egg.
6-Verification- the eggs are tested next morning if they got fertilized or not.
7- Transfer of embryo- the embryo, which is chosen for transfer, is passed through the cervix into the uterus through transfer catheter. Normally one embryo is transplanted but in some cases, the transfer of more than one embryo can happen.
8- Pregnancy test- Pregnancy blood test is done after 2 weeks of embryo transfer to see if the ICSI procedure has been successful or not.
It usually takes about four weeks to six weeks for one cycle of ICSI to complete.
So, the couples must expect to spend half days at the clinic for both sperms as well as egg retrieval process.
- Once the retrieval procedure is finished, you will be asked to visit the clinic after two to five days later for completing the embryo transfer process.
It is advised to the women who are under 40 years of age to opt for at least three cycles of IVF either with or without ICSI process.
And if you are between 40 to 42 year age group and never had IVF procedure done before then you will be offered one full IVF cycle after the discussion of risks and implications involved during pregnancy at this age. (8)
1- Normally, an ICSI session along with the shots, monitoring, and implantation become physically and emotionally challenging to many women. Therefore, a proper care routine including a regular blood test and frequent monitoring is required after a session of ICSI.
However, the good thing is that one does not need to get hospitalized for a long period after ICSI.
2- The post care treatments can be done on an outpatient basis.
Nonetheless, women after ICSI are advised to stay away from physically and mentally draining activities for at least a week or so as considered by your doctor.
ICSI treatments are more successful than IVF treatment. It uses more advanced technology in which a high-quality sperm is selected and injected into the egg for fertilization. Approximately 50% to 80% of the eggs are fertilized by ICSI process. (9)
ICSI procedure for infertility treatment entails various benefits. However, it is not free of any potential risks. There are certain risks and benefits of ICSI which are discussed below:
- ICSI is beneficial for those couples, who have failed IVF earlier.
- It benefits couples who desire pregnancy post-vasectomy.
- ICSI is for those males who have a lower sperm count and mobility.
- Damage to embryos can happen during the transfer (10)
- Multiple births can be a problem after ICSI
- Gestational diabetes, low amniotic fluid levels and high blood pressure in the mother can also be seen as side effects of ICSI.
SOURCES AND REFERENCES:
- ^ What is intracytoplasmic sperm injection (ICSI)? | ReproductiveFacts Reproductivefacts.org, 15 July 2019
- ^ Intracytoplasmic Sperm Injection | Wikipedia En.wikipedia.org, 15 July 2019
- ^ What is ICSI? | Altora Health Altorahealth.com, 15 July 2019
- ^ Intracytoplasmic Sperm Injection (ICSI) - How is it Performed? | American Pregnancy Americanpregnancy.org, 15 July 2019
- ^ Why India Needs Icsi in the Coming Times | Times of India Timesofindia.indiatimes.com, 15 July 2019
- ^ Intracytoplasmic Sperm Injection (ICSI) | ASRM Asrm.org, 15 July 2019
- ^ What is Sperm Retrieval? | Urology Care Foundation Urologyhealth.org, 15 July 2019
- ^ How Long Does ICSI Treatment Take? | The Bump Thebump.com, 15 July 2019
- ^ Success Rates of Rescue ICSI | Fertility and Sterility Fertstert.org, 15 July 2019
- ^ Is ICSI Risky? | NCBI Ncbi.nlm.nih.gov, 15 July 2019
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